Brand Oncology Products

Product Details:

ALOXI (palonosetron HCI injection) is an antinausea medication also known as an antiemetic. In adults, ALOXI is used to help prevent symptoms of CINV in a single intravenous (IV) dose by blocking the effects of serotonin.

Depending on the type of chemotherapy you receive, your chance of experiencing CINV on the same day, known as acute CINV, can be very high. You may also experience delayed CINV in the days following your treatment. ALOXI is used to prevent both acute and delayed CINV in patients receiving moderately emetogenic chemotherapy and acute CINV in patients receiving highly emetogenic chemotherapy.

If you experience CINV during 1 chemotherapy cycle, you are more likely to experience CINV again during a later cycle. Speak to your healthcare provider on the importance of trying to prevent these symptoms before they start.

Product Details:

DARZALEX is supplied as a colorless to pale yellow preservative-free solution for intravenous infusion in single-dose vials. The pH is 5.5. DARZALEX must be diluted with 0.9% Sodium Chloride Injection, USP [seeDOSAGE AND ADMINISTRATION].

Each DARZALEX single-dose 20 mL vial contains 400 mg daratumumab, glacial acetic acid (3.7 mg), mannitol (510 mg), polysorbate 20 (8 mg), sodium acetate trihydrate (59.3 mg), sodium chloride (70.1 mg), and water for injection.

Each DARZALEX single-dose 5 mL vial contains 100 mg daratumumab, glacial acetic acid (0.9 mg), mannitol (127.5 mg), polysorbate 20 (2 mg), sodium acetate trihydrate (14.8 mg), sodium chloride (17.5 mg), and water for injection.

Product Details:

Uses :-Revolade Tablets is a medicine that may help to increase the number of platelets, a type of blood cell that helps to reduce or prevent bleeding Revolade Tablets may be used to treat a bleeding disorder known as idiopathic thrombocytopenic purpura (ITP) ITP is the condition of having a low platelet count (thrombocytopenia) ITP patients may suffer from an increased risk of bleeding Symptoms/signs patients with ITP may notice are petechiae pinpoint sized flat round red spots under the skin, purpura bruising, nosebleeds, bleeding gums and not being able to control bleeding if cuts or injuries occur Revolade also may be used to treat patients with hepatitis C virus (HCV) infections for the treatment of thrombocytopenia

Product Details:

Everolimus is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body. The Afinitor brand of everolimus is used to treat certain types of kidney cancer, breast cancer, or brain tumor. Afinitor is also used to treat certain types of advanced or progressive tumors of the stomach, intestines, or pancreas. Afinitor is usually given after other treatments have been tried without success. Afinitor is also used to treat non-cancerous (benign) tumors of the kidney in people with a certain genetic condition called tuberous sclerosis complex. This medication guide provides information about the Afinitor brand of everolimus. Zortress is another brand of everolimus used to prevent organ rejection after a kidney transplant. Everolimus may also be used for purposes not listed in this medication guide.

Product Details:

Alimta (pemetrexed) is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Alimta is used to treat non-small cell lung cancer after other cancer medications have been tried without successful treatment.

Alimta is also used with another medication called cisplatin to treat mesothelioma, a form of lung cancer associated with exposure to asbestos.

Alimta may also be used for purposes not listed in this medication guide.

Product Details:

Azacitidine is a type of drug called a hypomethylating agent. It works by switching off a protein called DNA methyltransferase. This switches on genes that stop the cancer cells growing and dividing. This reduces the number of abnormal blood cells and helps to control cell growth.

Product Details:

Beleodaq (belinostat) is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Beleodaq is used to treat peripheral T-cell lymphoma that has relapsed or has not responded to other treatments.

Beleodaq was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, non-small cell lung tumors responded to this medicine. However, it has not been shown that belinostat can improve symptoms or lengthen survival time.

Product Details:

Targretin® (bexarotene) is a member of a subclass of retinoids that selectively activate retinoid X receptors (RXRs). These retinoid receptors have biologic activity distinct from that of retinoic acid receptors (RARs). Each soft gelatin capsule for oral administration contains 75 mg of bexarotene.

Product Details:

Dactinomycin is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Dactinomycin is used to treat different types of cancers that affect the kidneys, uterus, testicles, bones, muscles, joints, and soft tissues. Dactinomycin is also used to treat solid tumors.

Dactinomycin may also be used for purposes not listed in this medication guide.

Product Details:

Ramucirumab injection is used alone or together with paclitaxel to treat advanced stomach or gastroesophageal junction cancer (cancer that has already spread) after a patient has received other cancer medicines. It is also used in combination with docetaxel to treat metastatic non-small cell lung cancer (cancer that has already spread) in patients who have received other cancer medicines. This medicine is also used in combination with folinic acid, 5-fluorouracil, and irinotecan (FOLFIRI) to treat metastatic colorectal cancer (cancer that has already spread) in patients who have received other cancer medicines.

Product Details:

Dacogen is indicated for treatment of patients with myelodysplastic syndromes (MDS) including previously treated and untreated, de novo and secondary MDS of all French-American-British subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocytic leukemia) and intermediate-1, intermediate-2, and high-risk International Prognostic Scoring System groups.

Product Details:

Elitek (rasburicase) is a recombinant urate-oxidase produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.

Rasburicase is a tetrameric protein with identical subunits. Each subunit is made up of a single 301 amino acid polypeptide chain with a molecular mass of about 34 kDa. The drug product is a sterile, white to off-white, lyophilized powder intended for intravenous administration following reconstitution with a diluent. Elitek is supplied in 3 mL and 10 mL colorless, glass vials containing rasburicase at a concentration of 1.5 mg/mL after reconstitution.

Elitek 1.5 mg presentation contains 1.5 mg rasburicase, 10.6 mg mannitol, 15.9 mg L-alanine, between 12.6 and 14.3 mg of dibasic sodium phosphate (lyophilized powder), and a diluent (1 mL Water for Injection, USP, and 1 mg Poloxamer 188).

Elitek 7.5 mg presentation contains 7.5 mg of rasburicase, 53 mg mannitol, 79.5 mg L-alanine, and between 63 and 71.5 mg dibasic sodium phosphate (lyophilized powder) and a diluent (5 mL Water for Injection, USP, and 5 mg Poloxamer 188).

Product Details:

Folotyn is a medicine that contains the active substance pralatrexate. It was to be available as a solution for infusion (drip into a vein).
Folotyn was expected to be used to treat adults with peripheral T-cell lymphoma, which is a cancer of a type of white blood cell called T-cells.

Product Details:

Folotyn (pralatrexate injection) is an antineoplastic (anti-cancer) drug used to treat T-cell lymphoma that has spread throughout the body. Folotyn is given for relapsed T-cell lymphoma, or after other medications have been tried without successful treatment.

Product Details:

GILOTRIF is a prescription medicine used to treat people with non-small cell lung cancer (NSCLC):

• that has certain types of abnormal epidermal growth factor receptor (EGFR) genes. Your doctor will perform a test to check for certain types of abnormal EGFR genes, and make sure that GILOTRIF is right for you. GILOTRIF may be used when you have not had previous treatment for cancer that has spread to other parts of the body. It is not known if GILOTRIF is safe and effective in treating lung cancer with other abnormal EGFR genes.

Product Details:

HALAVEN is a prescription medicine used to treat adults with breast cancer that has spread to other parts of the body, and who have already received other types of anticancer medicines after the cancer has spread.

Product Details:

Lartruvo (olaratumab) injection is a platelet-derived growth factor receptor alpha (PDGFR-a) blocking antibody indicated, in combination with doxorubicin, for the treatment of adult patients with soft tissue sarcoma (STS) with a histologic subtype for which an anthracycline-containing regimen is appropriate and which is not amenable to curative treatment with radiotherapy or surgery.

Product Details:

IMLYGIC® has been genetically modified to replicate within tumors and to produce the immune stimulatory protein granulocyte-macrophage colony-stimulating factor (GM-CSF). When IMLYGIC® is injected into melanoma tumors, it causes lysis of tumor cells followed by release of tumor-derived antigens, which together with virally derived GM-CSF may promote an antitumor immune response. However, the exact mechanism of action is unknown.1

Product Details:

Istodax (romidepsin) blocks certain enzymes in the body and interferes with the growth of tumor cells.

Istodax is used to treat T-cell lymphoma affecting the skin (cutaneous T-cell lymphoma, or CTCL). It is usually given after other medicines have been tried without successful treatment of symptoms.

Istodax may also be used for purposes not listed in this medication guide.

Product Details:

Ixempra is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Ixempra is classified as an "antimicrotubule agent" or an "epothilone B analog".

What Ixempra Is Used For:

Ixempra is used in the treatment of metastatic or locally-advanced breast cancer.

Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.

How Ixempra Is Given:

• Ixempra is given as an infusion into the vein (intravenous, IV).
• The amount of Ixempra that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition you have. Your doctor will determine your exact Ixempra dosage and schedule.